Solution
Peripheral Component Interconnect Express (PCIe) is designed to be both forward and backward compatible across its generation. This means that even though PCIe-8398 is a Gen 3 x16 card, it can be used in a PCI Gen 4 x16 slot. However, do take note that a Gen 3 card will work in a Gen 4 slot, but it will operate at Gen 3 speed. Similarly, a Gen 4 card in a Gen 3 slot will be limited to Gen 3 performance.