Solution
The wireless transmission distance can be added by increase the power range of PXIE-S5090.
For example, the default power range of test port output (300 kHz to 6.5 GHz) is +13 to +15dBm, assume that increase to +20 to +30dBm can fulfilled the distance requirement, and external power amplifiers can be connected to PXIE-S5090.
However, amplifiers are one way devices which means that the signal can be amplified in one direction. This characteristic will cause the Rx signal to fail to pass through the power amplifier in the reverse direction, so the S11 not able to be measured.
When measuring S21, the external couplers are needed to measure the reflection from the Antenna. The port 2 to receive reflected signal is needed because PXIE-S5090 don't have direct receiver access (DRA). Measurement setup does not have to be this with DRA VNAs.
Based on how much power the coupler couples to the port 2, need optional attenuator to make sure VNA does not compress or be damaged. With this setup, the S11 measurement of antenna will be S21 on the VNA.