Solution
If you need to enable niDigital Configure Trigger VI, you could build a pattern which only has comparison vector in the pattern.
After you get source complete event from PXIe-4163, you start to burst this pattern by trigger source.
Then you can use niDigital PPMU Measure VI to measue the voltage or current on the comparison pin even if the pin function is not set to PPMU.

Example VI as below.
